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Postdoctoral Fellowship Opportunity - Computational Biology

The Rheumatology Department is looking for a talented computational biologist to join the Rheumatic Disease Functional Genomics Program on the Chicago campus of Northwestern University led by Drs. Harris Perlman and Deborah Winter. The program combines cutting-edge experimental technology and molecular techniques with innovative computational analysis and modelling.

Qualified candidates will work as part of a collaborative, interdisciplinary team collecting functional genomics data, including RNA-seq, ChIP-seq and ATAC-seq, to study the role of myeloid cells and other immune cells in the pathogenesis of rheumatic disease. Projects include both mouse models of disease and patient samples. They are interested in relating genomic analysis with genetic, phenotypic, or clinical data.

The position includes working closely with experimental and clinical researchers, balancing multiple research projects, and adapting new computational techniques as needed. Relevant expertise includes machine learning, software design, experience with high-performance computing clusters, network analysis, integration of high-throughput data, familiarity with common bioinformatic tools and software, database management, human genetics, epigenomics, clinical data mining, single-cell transcriptomics, and graphical/web-based programming.

  • Highly motivated individuals with a PhD or equivalent in computational biology or a related field and demonstrated strong background in computer science.
  • Applicants should have significant experience with one or more programming language (ex. Perl, Python, Java, etc.) and statistical environment (ex. R or Matlab).
  • Prior experience with computational research in a biological context (although not necessarily in immunology or rheumatology) is required and practice in handling transcriptomic and epigenomic data is preferred.
  • Candidates should have a good command of the English language, should be available for an interview, and must be eligible to work in the US.

Interested applicants should send a cover letter explaining relevant work experience (max 1 page), curriculum vitae and the names, telephone numbers and e-mail addresses of three references by e-mail to Erica Zuniga at

Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, underrepresented racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.