Postdoctoral Research Opportunity – CNS Regenerative Medicine Research
The Department of Neurological Surgery at Northwestern University is seeking outstanding postdoctoral fellows for expansion of basic and translational studies related to iPSCs, neural stem cells, CRISPR engineering, and devices for the treatment of spinal cord and brain injuries in vitro, in animal models, and for translational studies.
This position offers an opportunity to work in the lab of Dr. Christopher Ahuja, MD PhD FRCSC FAANS, a neurosurgeon-scientist with a background in stem cell research, genetic engineering, animal modeling of CNS injury, and high-throughput omics. The Ahuja lab has a strong translational emphasis and relies largely on human cells, clinically relevant models, and next-generation genetic engineering along with cutting-edge technologies such as spatial and single-cell transcriptomics, whole genome CRISPR screens, and AI-augmenting imaging for advancing our projects. Most projects involve cell culture, animal work, and analysis of specimens with advanced techniques. The lab has strong collaborations with expert groups in complementary fields including the Department of Neurosurgery and Dr. Maciej Lesniak’s lab (Neurosurgery Chairman; Northwestern University), the McCormick School of Engineering, and the Kellogg School of Management. The department offers a nurturing environment for career development, a stimulating community of CNS research labs, weekly conferences and seminars of interest.
The postdoctoral fellow will be expected to build a publication record including submissions to leading cell and translational medicine journals; supervise rotating undergraduate, graduate and medical students; apply for internal and/or extramural funding; and attend national meetings that will help to build an international reputation.
Minimum Qualifications: PhD in cell biology, biochemistry, gene therapy or neuroscience.
Required Competencies:
- Experience working with small animal models and mammalian cell culture
- Ability to design and conduct experiments, maintain accurate GLP style recordkeeping, and collaborate effectively within a team environment
- Strong written communication skills including grant drafting
- Ability to prepare and present research at meetings and write scientific manuscripts in fluent English
Preferred Competencies:
- Expertise in immortal cell culture
- Plasmid preparation, virus packaging
- Western blot, immunohistochemistry, immunocytochemistry, qPCR
- Familiarity with next generation sequencing data and gene expression analysis
- CRISPR, gene silencing and over-expression techniques
- R, python, or equivalent
To apply: Interested applicants must send a current curriculum vitae, a cover letter containing a short summary of research experience and aspirations, and names and contact information for at least three professional references to Dawn Rose.
Applicant must be able to begin employment no later than August 2025.