Postdoctoral Research Opportunity – The Green Lab in the Division of Gastroenterology and Hepatology and Comprehensive Transplant Center
The Richard Green Laboratory in the Division of Gastroenterology and Hepatology and the Comprehensive Transplant Center at the Northwestern University Feinberg School of Medicine seeks a postdoctoral fellow for an NIH-funded position. Investigations will utilize iPSC-hepatocytes and liver organoids to determine the pathogenesis of non-alcoholic steatohepatitis (NASH). NASH is a leading cause of cirrhosis and liver failure and there are no effective medical therapies or biomarkers for disease progression.
Our research approaches include developing iPSCs from affected patients and then differentiating the iPSCs into iPSC-hepatocytes and hepatic organoids. Investigations will focus on ER stress and the unfolded protein response, FXR-pathway signaling, and cell-matrix interactions. These basic and translational research studies use a range of cell and molecular approaches to study in vitro cell differentiation, protein and gene expression, mechanisms of transcriptional regulation, lipid biochemistry, and several omic approaches.
This position begins in June 2024 and is available for a minimum of two years with an opportunity for renewal pending satisfactory performance. Salary and benefits are competitive. Applications will be reviewed until the position is filled.
Qualifications for candidates:
- Strong interest and prior record of conducting basic or translational research
- Highly motivated individual with a PhD, MD, or equivalent degree
- Interest in the molecular and cell biology of liver disease pathogenesis, and the development of biomarkers and therapeutics
- A minimum of one first-author publication
- Excellent writing and communication skills
- Ability and desire to work in a highly collaborative and transdisciplinary environment
Applications should contain:
- Cover letter
- Statement of research interests, qualifications, and career goals
- Curriculum vitae (including publications list)
- Names and contact information of 3 references
Interested applicants should email their application to Richard M. Green, MD at r-green2@northwestern.edu.