Postdoctoral Training Opportunity - Neurology
Lab profile
The Kalb Lab is a neuroscience lab, which focuses on two topics: 1) The healthful compensatory responses of cells and organisms to stressful conditions and 2) activity-dependent development of circuits in the central nervous system.
Description
A postdoctoral research scholar is needed for a neuroscience lab at Northwestern University Feinberg School of Medicine, Department of Neurology.
The Kalb Neuronal Biology Laboratory uses genetically manipulated mice, primary neuron tissue culture, iPS cell-derived neurons, and C.elegans in their studies; our approach is cell and molecular biology. The lab's ongoing work on neurodegenerative diseases aims to identify molecular targets to ameliorate the toxicity of TDP43 and DPRs associated with C9ORF72 mutations. A postdoctoral trainee is needed to interrogate the biochemical, cellular, and behavioral phenotypes of mouse models of ALS with target gene manipulation.
The position is supported by the Department of Defense and the US Public Health service. Salary will be commensurate with experience.
To see some of their recent work, please see the journal articles below:
- Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance
- The Proline/Arginine Dipeptide from Hexanucleotide Repeat Expanded C9ORF72Inhibits the Proteasome
- Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization
Requirements:
Ph.D. degree in a relevant specialty such as biochemistry, cell biology, or pharmacology
The applicant should be an individual with cell and molecular biology skills and deep interest in protein homeostasis and neurodegenerative diseases. A publication track record of experience in this realm is mandatory.
Interested Candidates should e-mail a single PDF with a cover letter briefly describing their research interests and qualifications, a curriculum vitae, as well as the names and contact information for three references to Telicia Moore at telicia.moore@northwestern.edu.
Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, underrepresented racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.